주요발표
수상
학력
1995. 02 B. S./M. S. in Chemistry ( Ajou University )
2006. 08 Ph. D. in Bioorganic Chemistry ( POSTECH )
2006. 08 Ph. D. in Bioorganic Chemistry ( POSTECH )
경력
1995.08 - 2003.02
Senior Research Chemist, Isu Chemical Co.,
2003.03 - 2004.02
Researcher, Pohang University of Science and Technology (POSTECH)
2006.08 - 2007.01
Postdoctoral Researcher, Pohang University of Science and Technology (POSTECH)
2007.02 - 2010.07
Postdoctoral Researcher, The Scripps Research Institute(TSRI)
2010.07 - 2012.08
Research Associate, Brookhaven National Laboratory(BNL)
2014.02 - 2016.02
대한화학회 전북지부 간사장
2015.02 – Present
한국핵산학회 이사
2018.01-2018.12
분자세포생물학회 리보핵산 분과 재무 운영위원
2018.01-2018.12
대한화학회 생명화학 분과 운영위원
2012.09-2016.08
전북대 화학과 조교수
2016.09 - present
전북대 화학과 부교수
Senior Research Chemist, Isu Chemical Co.,
2003.03 - 2004.02
Researcher, Pohang University of Science and Technology (POSTECH)
2006.08 - 2007.01
Postdoctoral Researcher, Pohang University of Science and Technology (POSTECH)
2007.02 - 2010.07
Postdoctoral Researcher, The Scripps Research Institute(TSRI)
2010.07 - 2012.08
Research Associate, Brookhaven National Laboratory(BNL)
2014.02 - 2016.02
대한화학회 전북지부 간사장
2015.02 – Present
한국핵산학회 이사
2018.01-2018.12
분자세포생물학회 리보핵산 분과 재무 운영위원
2018.01-2018.12
대한화학회 생명화학 분과 운영위원
2012.09-2016.08
전북대 화학과 조교수
2016.09 - present
전북대 화학과 부교수
연구분야
연구업적
1. A. Pandith, R.G.Siddappa, Y. J. Seo "Recent Developments in Novel Blue/Green/Red/NIR Small Fluorescent Probes for In Cellulo Tracking of RNA/DNA G-Quadruplexes" Journal of Photochemistry & Photobiology,C: Photochemistry Reviews, 2019, 40, 81-116
2. B. H. Le, V. T. Nguyen, Y. J. Seo "Site-specific incorporation of multiple units of functional nucleotides into DNA using a step-wise approach with polymerase and its application to monitoring structural changes" , Chem. Commun, 2019, 55, 2158.
3. A. Pandith, K. R. Bhattarai, R. K. Guralamatta Siddappa, H-J. Chae, and Y. J. Seo "Novel Fluorescent C2-Symmetric Sequential On-Off-On Switch for Cu2+ and Pyrophosphate and Its Application in Monitoring of Endogenous Alkaline Phosphatase Activity", Sensors & Actuators: B. Chemical. 2019. 282, 730.
4. B. H. Le , and Y. J. Seo* "Highly sensitive microRNA 146a detection using Gold Nanoparticle-based CTG repeat Probing system and Isothermal Amplification" Analytica Chimica Acta, 2018, 999, 155.
5. H. N. Joo and Y. J. Seo* "Multiplex Fluorophore Molecular Beacon; Detection of Target sequence Using Large Stokes Shift and Multiple Emission Signal Properties", Chem. Commun, 2015, 51, 2939.
6. D. G. Lee, I. S. Kim, J. W. Park, Y. J. Seo*, "Multiplexed fluorophore systems on DNA (MFD) with New Diverse Fluorescence Properties and Ability to Sense Hybridization Dynamics", Chem. Commun, 2014, 50, 7273.
7. J. W. Park, B. H. Kim and Y. J. Seo "Fluorescence modification of the AAAA (4A) loop: Toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene' Chem. Commun., 2014, 50, 52.
8. Y.J.Seo, D. A. Malyshev, T. Lavergne, P. Ordoukhanian, and F. E. Romesberg, “Site Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs” J. Am. Chem. Soc. 2011,133, 19878 (this paper highlights my research).
9. D.A.Malyshev, Y.J.Seo, P.Ordoukhanian, and F.E.Romesberg, “PCR With an ExpandedGenetic Alphabet,” J.Am.Chem.Soc.2009, 131, 14620.
10. Y.J.Seo and F. E. Romesberg, “Major Groove Derivatization of an Unnatural Base Pair,” ChemBioChem. 2009, 10, 2394. (cover picture)
11. Y.J.Seo, M. Shigeo, and Floyd E. Romesberg, “Transcription of an Expanded Genetic Alphabet,” J. Am. Chem. Soc. 2009, 131, 5046.
12. Y.J.Seo, G. T. Hwang, P. Ordoukhanian, and F. E. Romesberg, “Optimization of an Unnatural Base Pair,” J. Am. Chem. Soc. 2009, 131, 3246.
13. N. Venkatesan, Y.J.Seo, and B. H. Kim, “Quencher free Molecular Beacons: A New Strategy in Fluorescence based Nucleic Acids Analysis,” Chem. Soc. Rev. 2008, 37, 648.
14. Y.J.Seo, I. J. Lee, J. W. Yi, and B. H. Kim, “Probing the Stable G-Quadruplex Transition Using Quencher-Free End-Stacking Ethynyl Pyrene-Adenosine,” Chem. Commun. 2007, 2817.
15. Y.J.Seo, H. Rhee, T. Joo, and B. H. Kim, “Self-Duplex Formation of an APy-Substituted Oligodeoxyadenylate and Its Unique Fluorescence,” J. Am. Chem. Soc. 2007, 129, 5244.
16. Y.J.Seo, S. Bhuniya, and B. H. Kim, “Reversible Sol–Gel Signaling System with epMB for the Study of Enzyme and pH-Triggered Oligonucleotide Release from a Biotin Hydrogel,” Chem. Commun. 2007, 1804.
17. Y.J.Seo and B. H. Kim, “Probing the B-to-Z-DNA Duplex Transition Using Terminally Stacking Ethynyl Pyrene-Modified Adenosine and Uridine Bases,” Chem. Commun. 2006, 150.
18. Y.J.Seo, J. H. Ryu, and B. H. Kim, “Quencher Free, End Stacking Oligonucleotides for Probing Single-Base Mismatches in DNA,” Org. Lett. 2005, 7, 4931.
2. B. H. Le, V. T. Nguyen, Y. J. Seo "Site-specific incorporation of multiple units of functional nucleotides into DNA using a step-wise approach with polymerase and its application to monitoring structural changes" , Chem. Commun, 2019, 55, 2158.
3. A. Pandith, K. R. Bhattarai, R. K. Guralamatta Siddappa, H-J. Chae, and Y. J. Seo "Novel Fluorescent C2-Symmetric Sequential On-Off-On Switch for Cu2+ and Pyrophosphate and Its Application in Monitoring of Endogenous Alkaline Phosphatase Activity", Sensors & Actuators: B. Chemical. 2019. 282, 730.
4. B. H. Le , and Y. J. Seo* "Highly sensitive microRNA 146a detection using Gold Nanoparticle-based CTG repeat Probing system and Isothermal Amplification" Analytica Chimica Acta, 2018, 999, 155.
5. H. N. Joo and Y. J. Seo* "Multiplex Fluorophore Molecular Beacon; Detection of Target sequence Using Large Stokes Shift and Multiple Emission Signal Properties", Chem. Commun, 2015, 51, 2939.
6. D. G. Lee, I. S. Kim, J. W. Park, Y. J. Seo*, "Multiplexed fluorophore systems on DNA (MFD) with New Diverse Fluorescence Properties and Ability to Sense Hybridization Dynamics", Chem. Commun, 2014, 50, 7273.
7. J. W. Park, B. H. Kim and Y. J. Seo "Fluorescence modification of the AAAA (4A) loop: Toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene' Chem. Commun., 2014, 50, 52.
8. Y.J.Seo, D. A. Malyshev, T. Lavergne, P. Ordoukhanian, and F. E. Romesberg, “Site Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs” J. Am. Chem. Soc. 2011,133, 19878 (this paper highlights my research).
9. D.A.Malyshev, Y.J.Seo, P.Ordoukhanian, and F.E.Romesberg, “PCR With an ExpandedGenetic Alphabet,” J.Am.Chem.Soc.2009, 131, 14620.
10. Y.J.Seo and F. E. Romesberg, “Major Groove Derivatization of an Unnatural Base Pair,” ChemBioChem. 2009, 10, 2394. (cover picture)
11. Y.J.Seo, M. Shigeo, and Floyd E. Romesberg, “Transcription of an Expanded Genetic Alphabet,” J. Am. Chem. Soc. 2009, 131, 5046.
12. Y.J.Seo, G. T. Hwang, P. Ordoukhanian, and F. E. Romesberg, “Optimization of an Unnatural Base Pair,” J. Am. Chem. Soc. 2009, 131, 3246.
13. N. Venkatesan, Y.J.Seo, and B. H. Kim, “Quencher free Molecular Beacons: A New Strategy in Fluorescence based Nucleic Acids Analysis,” Chem. Soc. Rev. 2008, 37, 648.
14. Y.J.Seo, I. J. Lee, J. W. Yi, and B. H. Kim, “Probing the Stable G-Quadruplex Transition Using Quencher-Free End-Stacking Ethynyl Pyrene-Adenosine,” Chem. Commun. 2007, 2817.
15. Y.J.Seo, H. Rhee, T. Joo, and B. H. Kim, “Self-Duplex Formation of an APy-Substituted Oligodeoxyadenylate and Its Unique Fluorescence,” J. Am. Chem. Soc. 2007, 129, 5244.
16. Y.J.Seo, S. Bhuniya, and B. H. Kim, “Reversible Sol–Gel Signaling System with epMB for the Study of Enzyme and pH-Triggered Oligonucleotide Release from a Biotin Hydrogel,” Chem. Commun. 2007, 1804.
17. Y.J.Seo and B. H. Kim, “Probing the B-to-Z-DNA Duplex Transition Using Terminally Stacking Ethynyl Pyrene-Modified Adenosine and Uridine Bases,” Chem. Commun. 2006, 150.
18. Y.J.Seo, J. H. Ryu, and B. H. Kim, “Quencher Free, End Stacking Oligonucleotides for Probing Single-Base Mismatches in DNA,” Org. Lett. 2005, 7, 4931.
주요논문
저서
대표논문
특허
1. B. H. Kim, Y.J.Seo, G. T. Hwang, "Oligonucleotide for detecting target DNA or RNA", Kor. Patent 10-0885177(2009. 2. 17)
2. B. H. Kim, Y.J.Seo, and G. T. Hwang, “Oligonucleotide for Detecting Target DNA or RNA,” US Patent Pending 11/578,058 (2006. 10. 12).
3. 서영준 “ CTG DNA를 붙인 금 나노입자와 환형 DNA에 기반한 miRNA 탐지 기술” Kor. Patent 10-2017-0143447
2. B. H. Kim, Y.J.Seo, and G. T. Hwang, “Oligonucleotide for Detecting Target DNA or RNA,” US Patent Pending 11/578,058 (2006. 10. 12).
3. 서영준 “ CTG DNA를 붙인 금 나노입자와 환형 DNA에 기반한 miRNA 탐지 기술” Kor. Patent 10-2017-0143447